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Literature summary for 2.7.11.31 extracted from
- AMP-activated protein kinase in the grass carp Ctenopharyngodon idellus Molecular characterization, tissue distribution and mRNA expression in response to overwinter starvation stress (2020), Comp. Biochem. Physiol. B, 246-247, 110457 .
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| AMP | - |
Ctenopharyngodon idella |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ctenopharyngodon idella | A0A514YC25 | subunit AMPKgamma3; grass carp | - |
| Ctenopharyngodon idella | A0A515J4H7 | subunit AMPKalpha1; grass carp | - |
| Ctenopharyngodon idella | A0A515J4I2 | subunit AMPKbeta1a; grass carp | - |
| Ctenopharyngodon idella | A0A515J4I4 | subunit AMPKbeta1b; grass carp | - |
| Ctenopharyngodon idella | A0A515J4J0 | subunit AMPKgamma2a; grass carp | - |
| Ctenopharyngodon idella | A0A515J4J2 | subunit AMPKalpha2; grass carp | - |
| Ctenopharyngodon idella | A0A515J4J3 | subunit AMPKgamma2b; grass carp | - |
| Ctenopharyngodon idella | A0A515J4V2 | subunit AMPKbeta2; grass carp | - |
| Ctenopharyngodon idella | A0A515J4V7 | subunit AMPKgamma1; grass carp | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | - |
Ctenopharyngodon idella |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adipocyte | - |
Ctenopharyngodon idella | - |
| adipose tissue | - |
Ctenopharyngodon idella | - |
| brain | - |
Ctenopharyngodon idella | - |
| brain | highest expression of subunit AMPKbeta1a | Ctenopharyngodon idella | - |
| foregut | - |
Ctenopharyngodon idella | - |
| foregut | highest expression of subunit AMPKbeta1b | Ctenopharyngodon idella | - |
| gill | - |
Ctenopharyngodon idella | - |
| gill | highest expression of subunit AMPKbeta2 | Ctenopharyngodon idella | - |
| gill | highest expression of subunit AMPKgamma1 | Ctenopharyngodon idella | - |
| heart | - |
Ctenopharyngodon idella | - |
| heart | highest expression of subunit AMPKalpha2 | Ctenopharyngodon idella | - |
| heart | highest expression of subunit AMPKgamma2a | Ctenopharyngodon idella | - |
| heart | highest expression of subunit AMPKgamma3 | Ctenopharyngodon idella | - |
| hepatocyte | - |
Ctenopharyngodon idella | - |
| hepatopancreas | - |
Ctenopharyngodon idella | - |
| hepatopancreas | highest expression of subunit AMPKalpha1 | Ctenopharyngodon idella | - |
| kidney | - |
Ctenopharyngodon idella | - |
| muscle | - |
Ctenopharyngodon idella | - |
| muscle | highest expression of subunit AMPKgamma2b | Ctenopharyngodon idella | - |
| spleen | - |
Ctenopharyngodon idella | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 29230, subunit AMPKbeta1b, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 29620, subunit AMPKbeta2, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 30410, subunit AMPKbeta1a, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 38260, subunit AMPKgamma3, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 39130, subunit AMPKgamma1, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 55530, subunit AMPKgamma2a, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 60380, subunit AMPKgamma2b, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 62290, subunit AMPKalpha2, calculated from amino acid sequence | Ctenopharyngodon idella |
| ? | x * 64700, subunit AMPKalpha1, calculated from amino acid sequence | Ctenopharyngodon idella |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AMP-activated protein kinase | - |
Ctenopharyngodon idella |
| AMPK | - |
Ctenopharyngodon idella |
| AMPKalpha1 | subunit | Ctenopharyngodon idella |
| AMPKalpha2 | subunit | Ctenopharyngodon idella |
| AMPKbeta1a | subunit | Ctenopharyngodon idella |
| AMPKbeta1b | subunit | Ctenopharyngodon idella |
| AMPKbeta2 | subunit | Ctenopharyngodon idella |
| AMPKgamma1 | subunit | Ctenopharyngodon idella |
| AMPKgamma2a | subunit | Ctenopharyngodon idella |
| AMPKgamma2b | subunit | Ctenopharyngodon idella |
| AMPKgamma3 | subunit | Ctenopharyngodon idella |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Ctenopharyngodon idella | subunit AMPKbeta1a, calculated from amino acid sequence | - |
5.6 |
| Ctenopharyngodon idella | subunit AMPKbeta2, calculated from amino acid sequence | - |
5.6 |
| Ctenopharyngodon idella | subunit AMPKgamma3, calculated from amino acid sequence | - |
6 |
| Ctenopharyngodon idella | subunit AMPKgamma1, calculated from amino acid sequence | - |
6.1 |
| Ctenopharyngodon idella | subunit AMPKbeta1b, calculated from amino acid sequence | - |
6.3 |
| Ctenopharyngodon idella | subunit AMPKgamma2a, calculated from amino acid sequence | - |
6.6 |
| Ctenopharyngodon idella | subunit AMPKalpha1, calculated from amino acid sequence | - |
7.1 |
| Ctenopharyngodon idella | subunit AMPKalpha2, calculated from amino acid sequence | - |
7.3 |
| Ctenopharyngodon idella | subunit AMPKgamma2b, calculated from amino acid sequence | - |
9 |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Ctenopharyngodon idella | the expression of enzyme isoform AMPKalpha2 significantly increases in the hepatopancreas of fish exposed to 1 week of overwinter starvation conditions. The expression of isoform AMPKalpha2 significantly increases in the adipose tissue of fish exposed to 4 week of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of enzyme isoform AMPKbeta1b significantly increases in the hepatopancreas of fish exposed to 8 weeks of overwinter starvation conditions. The expression of isoform AMPKbeta1b significantly increases in the adipose tissue of fish exposed to 1 week of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of enzyme isoform AMPKbeta2 significantly increases in the hepatopancreas of fish exposed to 12 weeks of overwinter starvation conditions. The expression of isoform AMPKbeta2 significantly increases in the adipose tissue of fish exposed to 8 weeks of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of enzyme isoform AMPKgamma1 significantly increases in the hepatopancreas of fish exposed to 12 weeks of overwinter starvation conditions. The expression of isoform AMPKgamma1 significantly increases in the adipose tissue of fish exposed to 4 weeks of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of enzyme isoform AMPKgamma2a significantly increases in the hepatopancreas of fish exposed to 16 weeks of overwinter starvation conditions. The expression of isoform AMPKgamma2a significantly increases in the adipose tissue of fish exposed to 8 weeks of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of enzyme isoform AMPKgamma2b significantly increases in the hepatopancreas of fish exposed to 8 weeks of overwinter starvation conditions. The expression of isoform AMPKgamma2b significantly increases in the adipose tissue of fish exposed to 4 weeks of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of enzyme isoform AMPKgamma3 significantly increases in the hepatopancreas of fish exposed to 16 weeks of overwinter starvation conditions. The expression of isoform AMPKgamma3 significantly increases in the adipose tissue of fish exposed to 4 weeks of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of isoform AMPKalpha1 significantly increases in the hepatopancreas of fish exposed to 1 week of overwinter starvation conditions. The expression enzyme isoform AMPK alpha1 significantly increases in the adipose tissue of fish exposed to 4 weeks of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
| Ctenopharyngodon idella | the expression of various enzyme isoform AMPKbeta1a significantly increases in the hepatopancreas of fish exposed to 16 weeks of overwinter starvation conditions. The expression of isoform AMPKbeta1a significantly increases in the adipose tissue of fish exposed to 1 week of overwinter starvation conditions. The mRNA levels of enzyme isoforms in hepatocytes and adipocytes change significantly with in the first 24 h of exposure to the overwinter starvation conditions | up |
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